Protein name:
Radical S-adenosyl methionine domain-containing protein 2 ;
Alternative:
Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible ;Viperin ;
Organism:
Mouse (Mus musculus).
General Annotation
Sub Unit:
Interacts with FPPS.
Function:
Involved in antiviral defense. May impair virus budding by disrupting lipid rafts at the plasma membrane, a feature which is essential for the budding process of many viruses. Acts through binding with and inactivating FPPS, an enzyme involved in synthesis of cholesterol, farnesylated and geranylated proteins, ubiquinones dolichol and heme. Plays a major role in the cell antiviral state induced by type I and type II interferon. Inhibits replication of Sindbis virus.
Subcellular Location:
Endoplasmic reticulum membrane
Peripheral membrane protein
Cytoplasmic side
Probably associates with the cytosolic side of the endoplasmic reticulum.
Protein Attributes:
50:
MGMLVPTALA | ARLLSLFQQQ | LGSLWSGLAI | LFCWLRIALG | WLDPGKEQPQ |
100:
VRGEPEDTQE | TQEDGNSTQP | TTPVSVNYHF | TRQCNYKCGF | CFHTAKTSFV |
150:
LPLEEAKRGL | LLLKQAGLEK | INFSGGEPFL | QDRGEYLGKL | VRFCKEELAL |
200:
PSVSIVSNGS | LIRERWFKDY | GEYLDILAIS | CDSFDEQVNA | LIGRGQGKKN |
250:
HVENLQKLRR | WCRDYKVAFK | INSVINRFNV | DEDMNEHIKA | LSPVRWKVFQ |
300:
CLLIEGENSG | EDALREAERF | LISNEEFETF | LERHKEVSCL | VPESNQKMKD |
350:
SYLILDEYMR | FLNCTGGRKD | PSKSILDVGV | EEAIKFSGFD | EKMFLKRGGK |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Mouse
Rat
Bovine
Pig
ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
ELISA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
CLIA Kit for Mouse Radical S-adenosyl methionine domain-containing protein 2
Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Polyclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Monoclonal Antibody for Mouse Radical S-adenosyl methionine domain-containing protein 2
Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2
Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2
Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2
Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2
Protein for Mouse Radical S-adenosyl methionine domain-containing protein 2
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA];INDUCTION
strain :
C57BL/6 .
tissue :
Lymph node .
2.
"The transcriptional landscape of the mammalian genome."
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Science309:1559-1563(2005)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
C57BL/6J .
tissue :
Bone .
tissue :
Bone marrow .
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
4.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain :
NMRI .
tissue :
Mammary tumor .
5.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : NUCLEOTIDE SEQUENCE [MRNA] OF 3-362
6.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : TISSUE SPECIFICITY
7.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : INDUCTION
8.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
9.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION
10.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : SUBCELLULAR LOCATION
11.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
12.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION;SUBCELLULAR LOCATION;INTERACTION WITH IRAK1 AND TRAF6
13.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : FUNCTION